Exodora – Exosomes Dermal Complex 1x5ml plant exosomes

Official and exclusive distribution in Poland

PureMED is the sole authorised distributor of the Exodora brand (Euroresearch Srl) in Poland.

By purchasing from PureMED you are guaranteed product authenticity with full batch and expiry-date traceability.

This page covers the single ampoule 1×5 ml. The product is also available in the 5×5 ml clinic pack for practices running regular exosome therapies.

What are exosomes and why are they the future of aesthetic medicine?

Exosomes (more precisely: extracellular nanoscale vesicles, 30–150 nm) are a discovery that has revolutionised cell biology. Long dismissed as cellular "waste packets", we now know they are a key intercellular communication system present in every living organism.

Every cell secretes exosomes containing a unique "information package": signalling proteins, membrane lipids, mRNA and miRNA (micro-RNA) fragments. When exosomes bind to target cells (fibroblasts, keratinocytes), they deliver cellular instructions that alter gene expression — effectively reprogramming cell behaviour. This is a far more precise mechanism than traditional collagen stimulators.

In aesthetic medicine, exosomes are the fastest growing category — surpassing even PDRN and polynucleotides as the next generation of biostimulators.

Plant exosomes – how do they differ from animal and human exosomes?

Exodora Dermal Complex uses plant exosomes (PELNPs — Plant Exosome-Like Nanoparticles), which carry specific clinical and ethical advantages:

• Immunological safety — plant exosomes carry no human surface antigens or human pathogens. Risk of immune reactions is significantly lower than with human or animal-derived exosomes.
• Cross-species communication — research has shown that plant miRNAs can cross species barriers and regulate gene expression in human cells. This mechanism (known from dietary miRNA) is here applied in a targeted and controlled manner.
• Standardisation and reproducibility — plant exosomes can be produced under controlled conditions with excellent batch-to-batch consistency, without the ethical controversies associated with human or animal cell sourcing.
• Vegan certification — no animal-derived ingredients.

Houttuynia cordata – exosome properties

Houttuynia cordata (lizard tail, "fish herb") is a medicinal plant used in Asian medicine for centuries, rich in quercetin, rutin, isoquercitrin and other flavonoids. Exosomes from this plant carry:

• Anti-inflammatory action — specific miRNAs from H. cordata modulate NF-κB and COX-2 pathways, reducing skin inflammation at the transcriptional level.
• Antioxidant action — neutralisation of reactive oxygen species (ROS), protecting skin cells from oxidative stress and photoageing.
• Antimicrobial action — antibacterial and antiviral activity supporting skin barrier integrity.
• Fibroblast activation — indirect stimulation of collagen synthesis through regulation of pro-regenerative gene expression.

Oryza sativa – rice exosomes and their action in skin

Exosomes from Oryza sativa (rice) are a rich source of gamma-oryzanol, ferulic acid and ceramides — substances long known in dermatology as potent antioxidants and brightening agents:

• Brightening of pigmentation — inhibition of tyrosinase activity, reduction of melanin synthesis, evening of skin tone.
• Reinforcement of the lipid barrier — ceramides in rice exosomes support epidermal barrier integrity (TEWL ↓).
• Epidermal antioxidation — ferulic acid is one of the most potent plant antioxidants, acting synergistically with vitamins C and E.
• Soothing properties — reduction of redness and reactivity of sensitive skin.

The synergy of Houttuynia cordata exosomes (regenerative and anti-inflammatory) with Oryza sativa exosomes (brightening, antioxidation, barrier support) creates complementary, broad-spectrum action unavailable with a single exosome source.

Treatment results

• improved skin density and elasticity,
• smoothing of fine lines and wrinkles,
• intensive hydration and improved hydrolipidic barrier,
• stimulation of fibroblasts to synthesise collagen and elastin,
• reduction of pigmentation and uneven skin tone,
• reduction of inflammation and skin reactivity,
• antioxidant protection — free radical neutralisation,
• improved overall skin quality, radiance and appearance,
• extracellular matrix remodelling — rebuilding dermal structure.

Indications and treatment areas

• skin requiring intensive regeneration,
• loss of density, elasticity and tone,
• fine wrinkles and lines,
• dehydrated and lacklustre skin,
• pigmentation and uneven skin tone,
• sensitive and reactive skin, rosacea,
• anti-ageing therapy and photoageing prevention,
• support and amplification of results after other procedures (laser, peels, HIFU, RF).

Treatment areas: face, neck, décolletage, hands.

Treatment protocol

• Dosage: 1 ampoule (5 ml) per session.
• Standard cycle: 4–6 sessions at 7–14 day intervals.
• Maintenance treatments: 1 session every 4–6 weeks or as individually indicated.
• Administration techniques: needle mesotherapy (nappage, papules), microneedling (dermapen) or as a booster before/after procedures (laser, peels, RF).
• Application parameters and protocol should be determined by a qualified specialist.

Composition and package contents

• Plant exosomes — Houttuynia cordata: intercellular communication, anti-inflammatory, antioxidant, regenerative stimulation
• Plant exosomes — Oryza sativa: gamma-oryzanol, ferulic acid, ceramides — brightening, antioxidation, barrier reinforcement
• Hyaluronic acid — deep intradermal hydration
• Amino acids — building blocks of collagen and elastin
• Vitamins — antioxidant protection of skin cells
• Contents: 1 × ampoule 5 ml
• EAN: 8054953401102
• Manufacturer: Euroresearch Srl, Corso Venezia 5, 20121 Milan, Italy
• Leaflet: Download PDF leaflet ↓

Related products: Exodora Dermal Complex 5×5 ml and Exodora Hair Complex 1×5 ml (exosomes for the scalp).

Contraindications

• pregnancy and breastfeeding,
• active skin infections or inflammation at the injection site,
• hypersensitivity to any component of the product,
• skin damage,
• occurrence of irritation.

FAQ – questions and answers

How do Exodora's plant exosomes differ from human or animal exosomes?

Human exosomes (e.g. from stem cells or umbilical cord blood) carry stronger biological signalling but come with risks of immune reactions and ethical concerns about sourcing. Exodora's plant exosomes have an excellent immunological safety profile, are reproducible, vegan-certified and carry no risk of human pathogen transmission. They can cross-regulate human cell genes via plant miRNAs — with clinically documented efficacy.

How does Exodora Dermal Complex differ from Exodora Hair Complex?

Exodora Dermal Complex is for face, neck and décolletage mesotherapy — regeneration, collagen, hydration, anti-ageing. Exodora Hair Complex is dedicated to the scalp — hair growth stimulation, reduced hair loss, improved follicle condition. The formulas are tailored to the distinct biological environments and needs of each area.

How can Exodora exosomes be combined with other procedures?

Exosomes work exceptionally well as a post-procedure booster (after laser, RF, microneedling, chemical peels) — applied immediately after a procedure they accelerate healing and amplify regenerative effects. They can also be combined with other mesotherapy products including Nithya Synerlift or NITHYA Type I Collagen.

When are the results visible?

Improved hydration, radiance and reduced skin reactivity are visible after 1–2 sessions. Full regenerative effects (density, elasticity, skin tone) build throughout the 4–6 session cycle and continue to develop for 4–6 weeks after completion.

Is Exodora Dermal Complex suitable for sensitive skin and rosacea?

Yes — the anti-inflammatory profile of Houttuynia cordata exosomes and the soothing properties of rice exosomes (Oryza sativa) make this product particularly suitable for sensitive, reactive skin and rosacea. No chemical irritants, no BDDE cross-linking agents, no irritating alcohols.

This product may only be used by doctors and cosmetologists trained in aesthetic medicine and holding qualifications to perform injections or mesotherapy procedures. By purchasing this product you confirm that you hold the required professional qualifications.

• What are exosomes and why are they the future of aesthetic medicine?
• Plant exosomes – how do they differ from human and animal exosomes?
• Houttuynia cordata – exosome properties
• Oryza sativa – rice exosomes and their action
• Treatment results
• Indications and treatment areas
• Treatment protocol
• Composition and package contents
• Contraindications
• FAQ – questions and answers